Marcela Romero mentioned she struggled with fertility points, making an attempt for 3 years to conceive with no luck.In November 2022, Romero, of Fort Myers, Florida, mentioned she began taking the treatment Mounjaro for weight reduction.Round two weeks after beginning the treatment, Romero mentioned she found she was pregnant.She mentioned she discontinued Mounjaro after her being pregnant was confirmed, and 9 months later, in September 2023, gave beginning to a wholesome daughter.”She’s very comfortable, very smiley on a regular basis,” Romero instructed “Good Morning America” of her now 7-month-old daughter.Marcela Romero, of Fort Myers, Fla., holds her daughter, who was born in September 2023.ABC NewsRomero is a part of a rising variety of girls reporting they have been in a position to turn into pregnant after taking Mounjaro or different medicine used for weight reduction, together with Ozempic and Wegovy.The medicine have turn into well-liked over the previous two years to be used for weight reduction and diabetes, however now girls are talking out about utilizing the drugs whereas making an attempt to conceive.Anna Parker, of Peachtree Metropolis, Georgia, instructed “GMA” she started taking Mounjaro in January in hopes of dropping pounds earlier than beginning in-vitro fertilization, or IVF, to turn into pregnant.”I spoke to my gynecologist, and he or she agreed that I might take it and hopefully shortly shed extra pounds,” Parker mentioned. “Up to now I’ve misplaced about 12 kilos, and I am actually trying ahead to hopefully making a easy transition to implanting the newborn.”Anna Parker, of Peachtree Metropolis, Ga., mentioned she is hoping to shed extra pounds by taking Mounjaro to extend her possibilities of changing into pregnant.ABC NewsBoth Ozempic and Mounjaro are authorized by the U.S. Meals and Drug Administration to deal with Kind 2 diabetes, however some docs prescribe the treatment “off-label” for weight reduction, as is permissible by the U.S. Meals and Drug Administration.Wegovy, a medicine that accommodates the identical fundamental ingredient, semaglutide, as Ozempic, is FDA-approved for weight reduction.Editor’s PicksIn November, the FDA authorized Zepbound as a weight reduction administration remedy for individuals with weight problems, or those that are chubby with no less than one associated underlying situation, comparable to hypertension — the identical prescribing steerage as Wegovy. As a diabetes drug, Zepbound is offered beneath the model identify Mounjaro, as the 2 drugs include the identical lively ingredient, tirzepatide.The drugs work by slowing down motion of meals by the abdomen and curbing urge for food, thereby inflicting weight reduction.Unwanted effects of the medicine can embody extreme nausea and constipation.A field of Mounjaro is seen at Rock Canyon Pharmacy in Provo, Utah, March 29, 2023.George Frey/Reuters, FILEWhile there’s not but any clear proof that these medicine are the reason for being pregnant, these results could possibly be correlated to girls being at a wholesome weight that improves possibilities for fertility.As well as, the medicine can sluggish gastric emptying and make any oral drugs, together with contraceptives, much less efficient, which will increase the danger of an unintended being pregnant, in keeping with Dr. Jennifer Ashton, a board-certified OBGYN and weight problems medication doctor, and ABC Information’ chief medical correspondent.”We simply haven’t got information on using GLP-1 agonists in a pregnant inhabitants so we all the time err on the aspect of warning by way of trying on the dangers of beginning defects,” Ashton mentioned.Whereas some girls might discover success in dropping pounds on the drugs after which changing into pregnant, each docs and the medicine’ producers don’t advise taking the drugs whereas pregnant.”We have no idea precisely what the impact goes to be on the fetus, and so for that purpose there’s a basic advice that girls cease taking the drugs for no less than two to a few months previous to the time that they conceive,” Dr. Rick Paulson, professor of reproductive medication on the College of Southern California, instructed “GMA.”Novo Nordisk, the maker of Wegovy and Ozempic, suggests stopping the drugs no less than two months earlier than a deliberate being pregnant because of how lengthy the drug stays within the system.Eli Lilly, the maker of Mounjaro and Zepbound, says sufferers ought to inform their healthcare supplier in the event that they turn into pregnant whereas on the drugs, noting the influence on the unborn child is “not recognized.”The U.S. Meals and Drug Administration additionally says in its security profiles of those medicine that they shouldn’t be taken throughout being pregnant, noting there’s “inadequate information” out there.The FDA additionally explains that the medicine might trigger weight reduction, and that “weight reduction affords no profit to a pregnant affected person and will trigger fetal hurt.”The FDA recommends that individuals discontinue the drugs no less than two months earlier than they plan to turn into pregnant.Going off of the drugs must be executed beneath the supervision of a medical supplier, simply as once you begin the drugs.An individual who turns into pregnant unexpectedly whereas taking certainly one of these medicine ought to contact their healthcare supplier, who may also help them transition off the treatment and ensure they’re receiving correct maternal care.