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Picture of small batch Kombucha Tea fermenting within the lab. Credit score: Elizabeth Poindexter, The Graduate College at UNC-Chapel Hill, CC-BY 4.0 (creativecommons.org/licenses/by/4.0/)
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Picture of small batch Kombucha Tea fermenting within the lab. Credit score: Elizabeth Poindexter, The Graduate College at UNC-Chapel Hill, CC-BY 4.0 (creativecommons.org/licenses/by/4.0/)
In a brand new research, researchers discovered that the microbes in kombucha tea make adjustments to fats metabolism within the intestines of a mannequin worm species which might be much like the results of fasting. Robert Dowen on the College of North Carolina at Chapel Hill and colleagues, current these findings within the journal PLOS Genetics.
Kombucha is a sweetened, fermented tea beverage that has surged in recognition not too long ago, partly as a consequence of its supposed well being advantages, reminiscent of reducing blood stress, stopping most cancers and defending towards metabolic illness and liver toxins. These advantages are believed to come back from the drink’s probiotic microbes and their results on metabolism, however the related well being claims haven’t been effectively studied in people.
Dowen’s group investigated how microbes from kombucha tea impression metabolism by feeding them to the mannequin nematode worm C. elegans.
The researchers discovered that the yeast and micro organism colonize the worms’ intestines and create metabolic adjustments related to those who happen throughout fasting. The microbes alter the expression of genes concerned in fats metabolism, resulting in extra proteins that break down fat and fewer proteins that construct a sort of fats molecule referred to as triglycerides. Collectively, these adjustments cut back fats shops within the worms.
The brand new outcomes present insights into how probiotics in kombucha tea reshape metabolism in a mannequin worm species, and provide hints to how these microbes could also be impacting human metabolism.
It is essential to keep in mind that extra analysis is required to supply proof that people consuming kombucha expertise related results because the C. elegans mannequin studied right here—however these findings seem in keeping with the reported human well being advantages of kombucha, be aware the authors, and will inform the usage of the beverage in complementary well being care approaches sooner or later.
The authors add, “We had been shocked to search out that animals consuming a weight-reduction plan consisting of the probiotic microbes present in Kombucha Tea displayed lowered fats accumulation, decrease triglyceride ranges, and smaller lipid droplets—an organelle that shops the cell’s lipids—when in comparison with different diets. These findings counsel that the microbes in kombucha tea set off a ‘fasting-like’ state within the host even within the presence of ample vitamins.”
Extra data:
Kombucha Tea-associated microbes rework host metabolic pathways to suppress lipid accumulation. PLoS Genetics (2024). DOI: 10.1371/journal.pgen.1011003
Journal data:
PLoS Genetics